Endocrine Abstracts

Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited endocrinopathy characterized by tumours of the parathyroid glands, adenohypophyseal and pancreatic tumours. We present a case of a young, 24 years old female patient with a positive familial background for MEN1 (on the fathers’ side of the family). She is one of two sisters with determined heterozigocity of the MEN 1 gene (Exon 2, codon 111). At the age of 12, insulinoma of the head of the pancreas was diagnos...

Introduction: Hyponatremia is rarely reported as a delayed complication of transsphenoidal resection of pituitary adenoma. Severe hyponatraemia can cause potentially fatal conse-quences.Material and methods: A 34 year old patient was admitted as an urgent case at the Clinic of Endocrinology, with symptoms and signs of Addisonian crisis (dizziness, headaches, nausea, vomiting, hypotension), with muscular weakness and muscle aches, tingling hands and confu...

Parathyroidectomy for hyperparathyroidism can be complicated with development of Hungry Bone Syndrome (HBS), a constellation of profound hypocalcemia with hypomagnesemia and hypophosphatemia. The severity of this potential life-threatening condition is related to the extent of the parathyroid-mediated high-turnover bone disease. We present a case of a 59-year-old woman developing post-surgical HBS as a result of longstanding severe unrecognized primary hyperparathyroidism (PHP...